Experimental Studies on Bifid T Wave in Rats

Min Do HUH; Hisashi HIROSE; Shigeru SUGANO

doi:10.11276/jsvc1984.19.97

Min Do HUH, Hisashi HIROSE, Shigeru SUGANO

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JOURNAL FREE ACCESS

1986 Volume 19 Issue 19 Pages 97-102

DOI https://doi.org/10.11276/jsvc1984.19.97

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Published: 1986 Received: - Available on J-STAGE: September 17, 2009 Accepted: - Advance online publication: - Revised: -
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Date of correction: September 17, 2009 Reason for correction: - Correction: ABSTRACT Details: [in Japanese]

Date of correction: September 17, 2009 Reason for correction: - Correction: AFFILIATION Details: Wrong :
1) Department of Animal Environmental Physiology, Faculty of Agriculture, Th University of Tokyo

Right :
1) Department of Animal Environmental Physiology, Faculty of Agriculture, The University of Tokyo

Date of correction: September 17, 2009 Reason for correction: - Correction: CITATION Details: Wrong : 1) HUH, M. D., H. HIROSE, S. SUGANO and H. SAWAZAKI (1986): Genesis of bifid T wave in rats. Jpn. J. Vet. Sci., 48, 137-144.
3) BIBERMAN, L., R. N. SARMA and B. SURAWICZ (1971) : T-wave abnormalities during hyperventilation and isoproterenol infusion. Am. Heart J., 81, 166-174.
4) WENDKOS, M. H. and R. B. LOGUE (1946): Unstable T waves in leads II and III in persons with neurocirculatory asthenia. Am. HeartJ., 31, 711-723.
7) ADAMS, H. R. (1978): Adrenergic and antiadrenergic drugs. JONES, L. M., N. H. BOOTH and L. E. MCDONALD In veterinary pharmacology and therapeutics. 4 th ed., 105-135. Iowa State University Press, Ames, Iowa.
8) KATz, A. M.(1980): Physiology of the heart, 209-227, Raven Press, New York.
9) HAN, J., D. MILLET, B. CHIZZONITTI and K. G. MOE(1966): Temporal dispersion of recovery of excitability in atrium and ventricle as a function of heart rate. Am. Heart J., 71, 481-487.
10) HOFFMAN, B. F. and E. E. SUCKLING(1954): Effect of heart rate on cardiac membrane potentials and the unipolar electrogram. Am. J. Phy-siol., 179, 123-130.
11) HOFFMANN, B. F. and P. F. CRANEFIELD (1960): Electrophysiology of the heart, 1st ed., 75-210. Futura Publishing Company, New York.
12) AHNVE, S. and H. VALLIN (1982): Influence of heart rate and inhibition of autonomic tone on the QT interval. Circulation, 65, 435-439.
14) WALSH, R. R. (1969): Heart rate and its neural regulation with rising body temperature in anesthetized rats. Am. J. Physiol., 217, 1139-1143.
15) OSBORN, J. J. (1953): Experimental hypothermia: Respiratory and blood pH changes in relation to cardiac function. Am. J. Physiol., 175, 389-398.

Right : 1) HUH, M. D., H. HIROSE, S. SUGANO and H. SAWAZAKI (1986): Genesis of bifid T wave in rats. Jpn. J. Vet. Sci., 48, 137-144.
3) BIBERMAN, L., R. N. SARMA and B. SURAWICZ (1971) : T-wave abnormalities during hyperventilation and isoproterenol infusion. Am. Heart J., 81, 166-174.
4) WENDKOS, M. H. and R. B. LOGUE (1946): Unstable T waves in leads II and III in persons with neurocirculatory asthenia. Am. HeartJ., 31, 711-723.
7) ADAMS, H. R. (1978): Adrenergic and antiadrenergic drugs. JONES, L. M., N. H. BOOTH and L. E. MCDONALD In veterinary pharmacology and therapeutics. 4 th ed., 105-135. Iowa State University Press, Ames, Iowa.
8) KATZ, A. M.(1980): Physiology of the heart, 209-227, Raven Press, New York.
9) HAN, J., D. MILLET, B. CHIZZONITTI and K. G. MOE(1966): Temporal dispersion of recovery of excitability in atrium and ventricle as a function of heart rate. Am. Heart J., 71, 481-487.
10) HOFFMAN, B. F. and E. E. SUCKLING(1954): Effect of heart rate on cardiac membrane potentials and the unipolar electrogram. Am. J. Physiol., 179, 123-130.
11) HOFFMANN, B. F. and P. F. CRANEFIELD (1960): Electrophysiology of the heart, 1st ed., 75-210. Futura Publishing Company, New York.
12) AHNVE, S. and H. VALLIN (1982): Influence of heart rate and inhibition of autonomic tone on the QT interval. Circulation, 65, 435-439.
14) WALSH, R. R. (1969): Heart rate and its neural regulation with rising body temperature in anesthetized rats. Am. J. Physiol., 217, 1139-1143.
15) OSBORN, J. J. (1953): Experimental hypothermia: Respiratory and blood pH changes in relation to cardiac function. Am. J. Physiol., 175, 389-398.

Abstract

In order to elucidate whether or not changes in heart rate, arterial pressure and arterial blood gases and pH were directly related to the genesis of bifid T wave, some experiments with adult male Wistar rats anesthetized with urethan (1.25 g/kg, i.p.) were performed under normothermia, before and after the procedure of hypothermia and the administration of isoproterenol. The configuration of T wave was not markedly changed by the atrial-paced increase in heart rate in normothermic rats. Changes in arterial pressure, arterial blood gases and pH before and after cooling and the administration of isoproterenol were not in accordance with the appearance of the bifid T wave. From these results, it was concluded that the respective changes in heart rate, arterial pressure and arterial blood gases and pH were not directly related to the appearance of a bifid change of T wave.

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