A STUDY OF INVESTIGATION OF CADMIUM GENOTOXICITY IN RAT BONE CELLS USING DNA MICROARRAY

Ken-ichi OHBA; Youhei OKAWA; Yuki MATSUMOTO; Yasuhiro NAKAMURA; Hisayoshi OHTA

doi:10.2131/jts.32.107

Toxicogenomics/proteomics Report

A STUDY OF INVESTIGATION OF CADMIUM GENOTOXICITY IN RAT BONE CELLS USING DNA MICROARRAY

Ken-ichi OHBA, Youhei OKAWA, Yuki MATSUMOTO, Yasuhiro NAKAMURA, Hisayoshi OHTA

著者情報

ジャーナルフリー

2007 年 32 巻 1 号 p. 107-109

DOI https://doi.org/10.2131/jts.32.107

詳細

抄録

To examine the transcriptional responses of rat bone cells continuously exposed to cadmium, we performed DNA microarray analysis. Cadmium increased levels of expression of 13 genes, including genes for Spp1, and reduced those of 10 genes.

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