DNA microarray gene expression analysis of human vascular endothelial cells exposed to arsenite

Yasuyuki Fujiwara; Akiko Honda; Masahiko Satoh

doi:10.2131/jts.35.275

Toxicogenomics/proteomics Report

DNA microarray gene expression analysis of human vascular endothelial cells exposed to arsenite

Yasuyuki Fujiwara, Akiko Honda, Masahiko Satoh

著者情報

キーワード: Arsenite, DNA microarray, Human vascular endothelial cell, Atherosclerosis

ジャーナルフリー

2010 年 35 巻 2 号 p. 275-278

DOI https://doi.org/10.2131/jts.35.275

詳細

抄録

DNA microarray was used to monitor the transcriptional response of human brain microvascular endothelial cells (HBMEC) and human coronary artery endothelial cells (HCAEC) to sodium arsenite (iAs^III). iAs^III enhanced the expression of 10 and 6 genes, and reduced the expression of 45 and 20 genes in HBMEC and HCAEC, respectively. Among the 64 genes whose expression was changed in some way, HBMEC and HCAEC had 5 up-regulated and 12 down-regulated genes in common.

責任著者(Corresponding author)

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