The Journal of Toxicological Sciences
Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350
EFFECTS OF CHLOROPEPTIDE ON LIVER COMPONENTS AND SERUM ENZYME ACTIVITIES IN MICE
Teruo ITOEmiko KOSUGIMidori NIWAIchijiro ISHIKAWAYoshio UENO
著者情報
キーワード: serum enzymes
ジャーナル フリー

1981 年 6 巻 2 号 p. 105-113

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抄録

The subcutaneous administration of chloropeptide, a hepatotoxic cyclic pentapeptide of Penicillium islandicum Sopp, induced a marked enlargement of hepatic weight in mice. Chemical analysis revealed an increment of water content. Biochemical investigation resulted in marked elevation of serum enzyme activities such as transaminases, alcohol dehydrogenase, fructose-1-phosphate aldolase and lactate dehydrogenase.

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© The Japanese Society of Toxicology Headquarters
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