Journal of UOEH
Online ISSN : 2187-2864
Print ISSN : 0387-821X
ISSN-L : 0387-821X
Susceptibility of Gram-Negative Bacterial Isolates to Six β-Lactam and Two Aminoglycoside Antibiotics at Our University Hospital
Tadao TANABEToshiji KOBAYASHIShin-ichi YOSHIDAYasuo MIZUGUCHI
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JOURNAL FREE ACCESS

1988 Volume 10 Issue 3 Pages 297-303

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Abstract
Susceptibilities of Gram-negative bacterial strains isolated at the University Hospital in 1987 to six β-Lactam antibiotics (azthreonum cefmetazole, ceftizoxime, Iatamoxef, aminobenzyl-penicillin and piperacillin) and two aminoglycoside antibiotics (gentamicin and amikacin) were examined by agar dilution and the agar diffusion method. Results obtained from both methods correlated well in most of the strains. Most of the strains belonging to Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae and Proteus mirabilis were sensitive to the β-lactam antibiotics except aminobenzyl-penicillin and piperacillin. They were also sensitive to aminoglycoside antibiotics. Most strains of Citrobacter freundii Enlerobacter cloacae and Serratia marcescens were sensitive to azthreonum, Iatamoxef and aminoglycosides, but were less sensitive to other β-lactams. Acineiobacter calcoaceticus was generally resistant to β-lactams except ceftizoxime, but was sensitive to aminoglycosides. More than half of the strains of Pseudomanas aeruginosa were sensitive to azrhreonum, piperacillin and aminoglycoside antibiotics and only latamoxef was active in Pseudomanas maliophilia.
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© 1988 The University of Occupational and Environmental Health, Japan
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