Journal of UOEH
Online ISSN : 2187-2864
Print ISSN : 0387-821X
ISSN-L : 0387-821X
[Case Report]
Three Cases of Bacteremia due to Helicobacter cinaedi Infection and the Usefulness of Gene Analysis of Isolated Bacteria
Yosuke SASAHARA Shingo NOGUCHITakeshi ORIHASHIIkuko SHIMABUKUROTakaaki OGOSHIKazuhiro YATERAChiharu YOSHIIHiroshi MUKAE
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2015 Volume 37 Issue 4 Pages 293-298

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Abstract

Helicobacter cinaedi is typically isolated from immunocompromised patients. Some reports of infection caused by H.cinaedi have been found in recent years. We experienced three cases of H.cinaedi bacteremia in one year and ten months in our hospital, although the detection of H.cinaedi in blood cultures is extremely rare. In case 1, a 77-year-old female had been treated with a steroid and immunosuppressive agent for interstitial pneumonia. In cases 2 and 3, two 71-year-old men had been treated with chemotherapy for lung cancer. Although the identification of the bacteria could not be performed by the culture method in the three cases, H.cinaedi bacteremia was diagnosed by a 16S rRNA gene sequencing analysis in case 1, and by nested PCR in cases 2 and 3. H.cinaedi bacteremia often tends to recur and also requires prolonged antimicrobial therapy. We believe that gene analysis is useful in the identification of H.cinaedi.

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© 2015 The University of Occupational and Environmental Health, Japan
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