Abstract
A comparison of the effects of inhalation anesthesia with enflurane and halothane was studied. Clinical findings and blood examinations were recorded in the 13 healty dogs (8 of the 13 dogs anesthetized by enflurane, 5 of the 13 dogs by halothane) . The anesthetic procedures were as follows; the premedication with atropine sulfate (0.025 mg/kg, I.M. or S.C.) ; the induction by mask inhalation of the stepwisely increased agents in concentration with the carrier gas (25% O2, 75% N2O) ; and the maintenance with 1.0 to 3.0% enflurane or halothane with the same carrier gas. The period of anesthesia was 120 minutes.
There were no significant changes on the clinical findings during the anesthesia except that the mild depression of the mean arterial pressure and that mildly decreased resiratory rate in enflurane anesthesia.
The results of the blood examinations carried out daily for 10 days after the anesthesia showed slight increases of GOT, GPT and AlP values in the dogs with halothane anesthesia, whereas little changes of the values were observed in the dogs with enflurane anesthesia.
