Journal of Japan Veterinary Cancer Society
Online ISSN : 1884-3352
Print ISSN : 1884-3344
ISSN-L : 1884-3344
Original Article
Local Treatment for Canine Well-differentiated Maxillary and Mandibular Fibrosarcoma: 31 cases(1998-2007)
Takuo ShidaTakuya MaruoYasuhiro FukuyamaSoshi HosakaKoji HayashiRie ImaiTomomi YokoyamaToru YamadaTetsuro ItoHiroo Madarame
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JOURNAL FREE ACCESS

2010 Volume 1 Issue 3 Pages 45-51

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Abstract
Objectives: To assess the efficacy of local treatment for canine well-differentiated maxillary and mandibular fibrosarcomas.
Methods: A retrospective analysis of 31 case records was conducted to evaluate the differences in tumor-free survival time and overall survival time between treatment and no-treatment groups.
Results: The overall mean tumor size and median survival time for 29 dogs was 6.5 cm and 270 days, respectively. There was no significant difference between the tumor sites(p=0.420). A significant difference(p=0.008)was found in the median survival time between the local treatment group(592 days)and no-treatment groups(162days). In the subgroup analysis, a significant difference(p=0.027)was found in the median tumor-free survival time between the cases without radiation therapy(68 days)and those with radiation therapy(515 days). Local tumor progression(n=16)was one of the most common causes of death; yet, death was delayed with a combination of surgery and post hypofractionated radiotherapy.
Clinical Significance: The significantly shorter survival time of the no-treatment group confirmed the poor prognosis of canine well-differentiated maxillary and mandibular fibrosarcomas, when it is not treated. Carefully planned local treatment such as a combination of surgical excision and radiotherapy can ultimately extend survival time for this tumor.
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© 2010 Japan Veterinary Cancer Society
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