Small Animal Medicine
Economical Effect of Butorphanol or Morphine on Anesthetic Induction Dose of Aflaxalone for Endotracheal Intubation in Dogs
2018 Volume 71 Issue 2 Pages 99-104
Details
2018 Volume 71 Issue 2 Pages 99-104
The dose of alfaxalone (ALFX) required for endotracheal intubation was examined in a study of 42 dogs undergoing sterilization surgery. The dogs were classified based on whether they received intravenous butorphanol (BTR) (0.4 mg/kg) or subcutaneous morphine (MOR) (0.5 mg/kg) 15 minutes before anesthetic induction (pre-B and pre-M groups, respectively), or after intubation (post-B and post-M groups, respectively). The findings indicated that the doses of ALFX required for endotracheal intubation were 1.59±0.26 mg/kg in the pre-B group and 2.45±0.36 mg/kg in the post-B group, revealing a 35.1% reduction, and 1.30±0.38 mg/kg in the pre-M group and 2.42±0.52 mg/kg in the post-M group, revealing a 46.2% reduction (P＜0.05). The dose of ALFX required for endotracheal intubation was found to have decreased when ALFX was administered in combination with BTR or MOR.
