2019 Volume 72 Issue 9 Pages 555-559
Verrucous endocarditis and miliary nodules in and around the inner wall of the pulmonary artery were observed in a slaughtered pig that showed decreased growth, emaciation and cyanosis at an abattoir in Nagasaki prefecture, Japan in December 2017. Petechiae in the lung and kidney, hepatic congestion and splenomalacia were also recognized. Bacteriologically, only Actinobacillus pleuropneumoniae serovar 8 was isolated from the vegetation, heart, kidney and spleen. Histopathologically, suppurative necrotizing inflammation with oat cells was observed in the vegetation and the nodules of the pulmonary artery, and gram-negative bacteria were observed in necrotic areas. A. pleuropneumoniae serovar 8 antigens were detected in the necrotic areas by immunohistochemistry using antiserum raised against A. pleuropneumoniae serovar 8. The present case was finally diagnosed as verrucous endocarditis and pulmonary arteritis caused by A. pleuropneumoniae serovar 8.