A Case Report of Pyogranulomatous Panniculitis and Atrophic Dermatosis in a Cat with Pancreatic Adenocarcinoma and Adrenal Cortical Adenoma

Abstract

A 14-year-old, spayed female cat with a 4-year history of diabetes mellitus and skin fragility was presented with anorexia and lethargy. Despite symptomatic treatment for approximately one month, the cat died. At necropsy, skin atrophy and numerous yellowish white nodules were observed in the subcutaneous fatty tissue of the trunk. In addition, mass lesions were also observed at the pancreas and right adrenal gland. Histopathological examinations revealed pyogranulomatous panniculitis, atrophic dermatosis characterized by a thin epidermis, sparse collagen fibers and atrophic follicles and sebaceous glands, pancreatic adenocarcinoma and adrenal cortical adenoma. In this case, pyogranulomatous panniculitis and atrophic dermatosis were suspected to be associated with adrenal cortical adenoma and pancreatic adenocarcinoma, respectively.