Abstract
A 10-month-old Akita bitch and a 13-month-old shepherd male were suffering from the malabsorption syndrome. Laboratory tests revealed mild anemia, hypoproteinemia, and hypocholesteremia. A serious insufficiency in pancreatic enzymes was suggested. No diabetic signs were noticed, but a hypofunction of sugar decomposition was exhibited.
Pathologically, the pancreas was highly atrophic with principal changes in acinar cells. These cells contained pale unclei and slightly basophilic cytoplasm. Islands of langerhans remained unchanged. Electron microscopy revealed the presence of multivesicular cells with specific morphology. Nothing abnormal was seen in the pancreatic ducts, blood vessels, or peripheral nerves.