Abstract
Experimental hypocalcemia was induced in normal goats by intravenous administration with various concentrations of Na2-EDTA solution.
1. Progressive depression of reflexes and body temperature, paresis, and cardiac arrest were observed in two groups administered with 4% and 8% EDTA, respectively. They were not observed within 240 minutes after administration with 2, 2.5, or 3% EDTA.
2. The tissue calcium concentration was lower in all the goats which died after EDTA administration than in the normal one.
3. The tissue calcium concentration became much lower in the cerebral cortex than in the rectus femoris muscle after EDTA administration.
