Abstract
A total of 278 dogs were given orally with 0.025 to 1.0mg/kg of milbemycin D.Of them, 124 were infected with round worms, 79 with hook worms, and 75 with whip worms.Then 188 dogs were examined coprologically from 7 to 37 days after treatment.Of them, 90 were killed 7 days after treatment and examined for resident worms.
Of 62 dogs infected with round worms, 58 (0.1mg/kg) became free from these worms.Of 32 dogs infected with hook worms, 29 (0.025mg/kg) became free.Of the 75 dogs infected with whip worms, 60 (1.0mg/kg) became free.No side effects were observed in any dogs.