Abstract
A two-month-old miniature duchshund died of dyspnea. Histologically, basophilic intranuclear inclusion bodies were found in bronchiolar and alveolar epithlial cells and alveolar macrophages. Eosinophilic cytoplasmic inclusion bodies were observed in the cytoplasm of the bronchiolar epithelium. Electron microscopically, adenovirus particles were found in the nucleus and cytoplasm. Nucleocapsids of canine distemper virus were observed in the cytoplasm of the bronchiolar epithelium.