Abstract
A 2-year-old Holstein-Friesian dairy cow affected with skin leukosis was pathologically examined about 60 days after the first appearance of tumors. The cutaneous tumors measuring 2 to 7cm in diameter were observed on the neck, shoulder, back and abdomen, numbering about 850. At autopsy, the kidneys had discrete solid nodules 0.5-1.5 cm in diameter, and the abomasum had discrete greyish white nodules 2-5 mm in diameter. Microscopically neoplastic cells were observed in the skin, liver, kidneys, bone marrow, abomasum and lymph nodes (subparotideal, axillar, cervical superficial, prefemoral, popliteal, supramammary, iliac medial, sacral and tuberous ischii.) Most of these cells appeared to be lymphoblasts. In the skin, the epidermal eliminating phenomenon was observed in the dermis. Anti-BLV antibody was negative.
