Abstract
A 2.5-month-old, male Holstein-Friesian calf with ataxia and visual disturbance was subjected to electroencephalographic (EEG) and pathological examinations. The EEG in awake state revealed a wave pattern dominant in high amplitude (40-120 μV) slow waves during the whole period of recording, while almost normal pattern appeared transiently. The EEG in sleep state revealed a markedly high amplitude exceeding 200 μV. The animal was responsive to photic stimulations, but not to auditory ones. Microscopy revealed a widespread spongy degeneration throughout the central nervous system.