Levels of Vitamin A and E in Blood of Cows after Administration of Water-Soluble Granules of Vitamin AD₃E Premix

Abstract

Blood levels of vitamin A and E were examined in cows after administration of a new type water-soluble granule premix of vitamin AD₃E comparing with the conventional powder type. In animals given the watersoluble granule type either mixed in feed or injected by oral route, tocopherol levels markedly increased showing the same patterns, peaking in serum and red blood cells at 24 hrs. Serum retinylpalmitate levels also increased markedly showing a peak at 4 hrs. In cows given the powder type of the same vitamin content, increases of blood tocopherol and serum retinylpalmitate were slower and slight. A single dosing of the watersoluble granule type at 250, 000IU/100kg or more of vitamin A and 1, 000mg/100kg or more of vitamin E, was effective resulting in significant increase of the blood levels.