Abstract
The histopathological and immunohistochemical features of a tumor in the tail tip of a spayed female ferret (age 2.5 years) were evaluated. A mass, noted several months earlier by the owner to be growing slowly on the tail tip, was surgically removed. Histopathological examination showed it to be composed of multilobulated physaliferous cells, cartilage, and bone infiltrating the caudal vertebrae. Immunohistochemical examination showed it to be positive for vimentin and S-100 protein and partially positive for neuron-specific enolase. On the basis of these histopathological and immunohistochemical findings, the tumor was considered to be chordoma.
