Abstract
The canine parvovirus (CPV) excreted in the feces of dogs inoculated with live CPV vaccine and othernaturally infected dogs was examined by means of the Latex-agglutination test (LA test). The virus was isolated from the feces of the inoculated dogs, though none of them manifested clinical signs. In2 inoculated dogs, at 6 weeks of age, the LA test revealed no CPV-specific antigen; and the ELISA test detected low virus titers of from 2 to 5 units. In 2 of 4 dogs inoculated at 15 days of age, the LA test showed weak agglutination in undiluted feces solution. In the ELISA test, 4 dogs excreted virus titers of from 3 to 100 units. CPV was isolated from 7 animals manifesting severe clinical signs. The HA test on feces from these animals showed virus titers of from 1: 512 to 1: 4, 096; the LA test showed titers of from 1: 2 to 1: 512. These results suggest that, in small animal practice theLA test is useful in discriminating rapidly between CPV natural infection and CPV infection resulting from vaccination.
