Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
A Case of Canine Pituitary-dependent Hyperadrenocorticism Diagnosed with a Corticotropin Releasing Hormone
Yoshiaki NAGAYANaomi INOMATASeiji TARUIYoshimi NAKANOYoshiaki YONEKAWAShutaro TAKAHASHI
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JOURNAL FREE ACCESS

2001 Volume 54 Issue 1 Pages 30-33

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Abstract
On the basis of symptoms and blood-test findings, an 11-year-old, male dachshund with alopecia, polydipsia, and polyuria was suspected of hyperadrenocorticism. Adrenocorticotropic hormone (ACTH) testing confirmed the suspicion. Then a corticotropin releasing hormone (CRH)-stimulating test was conducted to determine whether hypercorticism in this case was pituitary-dependent. Because its plasma ACTH level was higher than normal after CRH administration, the affected dog was diagnosed as having pituitary-dependent hyperadrenocorticism. Moreover, histopathological examination revealed adenoma of the pituitary anterior lobe and hyperplasia of the adrenal cortex. These findings indicate that the CRH-stimulating test is useful in diagnosing canine pituitary-dependent hyperadrenocorticism.
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