Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Effectiveness of the β-adrenergic Blocker in a Feline Case of Hypertrophic Obstructive Cardiomyopathy (HOCM)
Osamu DOIGUCHIMasaru DOIGUCHI
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2003 Volume 56 Issue 4 Pages 261-264

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Abstract
Echocardiography revealed asymptomatic hypertrophic obstructive cardiomyopathy in a 2-year-old Persian cat initially submitted for dermal disease. Once curative improvement of the dermal disease had been achieved, a calcium channel blocker (Diltiazem) was administered for 284 days. When neither hemo-dynamics nor diastolic function improved, this drug was replaced with a β-adrenergic blocker (Atenolol). Observation for a further 562 days revealed improvement in diastolic function, reduced systolic anterior movement of the mitral valve, and alleviation of mitral regurgitation. Thereafter, amplitude of the left-ventricular outflow pressure gradient changed from 139mmHg to 7.2 mmHg; and hypertrophic septal thickness decreased from 0.75cm to 0.45cm.
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