Abstract
Uterine tumors in 16 sows (aged from 2 to 4 years) at a slaughterhouse were investigated macroscopically, histopathologically, and immunohistochemically. Located mainly in the uterine horn, tumors were solitary in 9 cases and multiple in 7 cases. In histological terms, they were composed of whirling and interlacing bundles of neoplastic cells with nuclei that were oval or elongated-oval with blunt, rounded ends. Since they were positive for desmin and of -smooth muscle actin in all cases and for vimentin in 13 of 15 cases (87%), the neoplastic cells were thought to be of smooth-muscle origin. In one case, 4 to 5 mitotic figures per 10 high-power magnification fields (X400) were detected; but mitotic activity was low in all other cases. The positive reaction rate of proliferating cell-nuclear antigen (PCNA) ranged from 0 to 85%. Paucity of mitoses and absence of metastasis indicated that the neoplasms were benign.
