Primary Splenic Lymphoma in a Cat

Abstract

An 11-year-old mongrel cat that was referred for depression and anorexia showed severe splenomegaly and pancytopenia. Because hematologic response to the administration of prednisolone was not noticeable, the cat underwent a splenectomy. After the splenectomy, the pancytopenia improved. Based on histopathologic and immtmohistochemical findings. the dissected spleen was diagnosed with B-cell lymphoma. In this case, lymphadenopathy was not observed. On the basis of these findings, we diagnosed primary splenic lymphoma. The Clinical course of the present case suggests a causal relationship between feline primary splenic lymphoma and pancytopenia.