Abstract
1. It is very difficult to produce cystitis in healthy animals by injection into the cyst of bloody urine containing abundant diplococci and other microorganisms, or of their pure cultures. The normal mucous membrane of cyst has very strong self-protective power against the invasion, or may probably soon recover from the slight lesion, and the normal urine has usually certain controlling power against some injurious microorganisms.
2. Two kinds of diplococcus isolated from the patient's urine, temporarily named “Diplococcus haematuriae bovis”, have no special aetiological meaning compared with other microorganisms and other urine ingredients.
But because these 2 kinds are most abundant and common, and they are also proved occasionally in the tissue or in cells of the inflammatory m. m. and the growth of the cyst, it may be said that they are more serious actors than the other several changeable and unstable microorganisms and ingredients in introducing as well as promoting the cystitis.
3. There are several factors (see above) which may contribute to produce the cystitis but the actual irritants of the urocystitis haemorrhagica are not yet decided.
