1973 Volume 35 Issue 5 Pages 411-418
Effect of vaccination against Bordetella bronchiseptica infection in pigs was studiedby using thimerosal-killed Phase I organisms. After naturally infected 15-week-old con-ventional piglets were given two or three doses of vaccine subcutaneously, their agglutinat-ing antibody titers attained a level of l : 10, 000 to l : 80, 000. B. bronchiseptica harboredin the nasal cavities, however, remained persistently in these piglets at the same level asin the unimmunized control piglets throughout the experimental period.When pregnant sows were injected subcutaneously with 2 doses of the vaccine 4 to6 weeks before parturition, they showed an agglutinating antibody titer ranging froml : 10, 000 to l : 20, 000 at parturition. The colostrum-fed piglets born from these sowspresented an antibody titer of 1 : 10, 000 or higher. Seven days after birth they resistedthe nasal establishment of B. bronchiseptica.
