日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
Online ISSN : 1881-1442
Print ISSN : 0021-5295
ISSN-L : 0021-5295
広東住血線虫感染に対するモルモットの免疫応答
吉村 堅太郎山岸 豊子
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ジャーナル フリー

1975 年 37 巻 6 号 p. 585-591

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抄録
Guirxea pigs infected witlt Angiostrongylus cantonensis were examined forthe occttrrence of antigen sensitixe lymphocytes in variotns lymphoid organs (cervical, mediastinal and mesenteric l)mph nodes, and spleen), as assessed by in vitro incorpora-Lion of tritiated thymidine by lymphocytes following stimulation by adult or young adultworm antigens.Only splenic cells from infected guinea pigs showved significant blastogenic responses toboth adult and young adult worm antigens throtughout the course of infection. Thisresponse gradually increased as the infection progressed.Homocytotropic reaginic antibody was first detected 18 days postinfection and continu-ously demonstrated in some individuals throughout 18 to 47 days postinfection. However, the production of reaginic antibody was observed in only 50% (5/10) of the infectedanimals.No hemagglutinating antibody could be observed in the infected animals during thecourse of infection.
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© 社団法人 日本獣医学会
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