Abstract
Biochemical properties of feline herpesvirus (FIIV) hemagglutinin obtainedfrom infected feline lung cell (FLC) cultures and receptors on feline erythrocytes were in-vestigated. Generally, a close parallelism was shown to exist between the infectivity andhemagglutination (H, X) activity of fresh and crude FIIV suspensions. When FHV suspen-sion was held at 37C, its HA activity was slightly enhanced and maintained, while itsinfectivity was reduced. The HA Liter of the virus fluid supplemented with polyoxyethylencsorbitan mono-oleate (Tween 80) ahead of ethyl ether treatment was 2 to 4 times higherthan that of the virus fluid without Tween 80. Hemagglutinin was proved to be associatedwith the viral envelope. Viral hemagglutinin obtained by Tween 80-ether treatmentpossessed the character of a glycoprotein. A large quantity of hemagglutinin which wasnot always considered to be derived from the mature virion was also detected in the in-fected FLC. The agglutinability of the feline erythrocyte was inactivated by the trypsintreatment. Discussion was made on the HA reaction of FIIV in comparison with that ofequine abortion and measles viruses.
