Parvoviral Myocarditis in Cyclophosphamide-treated Chicks

Abstract

Acute to subacute parvoviral myocarditis occurred in 6 chicks which had been previously treated with cyclophosphamide during preliminary experiments on an chicken anemia agent. Myocarditis was constantly associated with inclusion bodies in nuclei of the myocardial fibers. The inclusions contained numerous viral particles which were approximately 20 nm in diameter, and morphologically identical to parvovirus.