Abstract
Astrocytoma occurring in the thoracic spinal cord was found in a male 74-week-old Sprague-Dawley rat. Histologically, the densely proliferating neoplastic cells were polyhedral in shape and had hyperchromatic oval nuclei and relatively scanty cytoplasm with apparent glial fibers. Some of the cells were positive in the immunohistochemical method to glial fibrillary acidic protein (GFAP). Ultrastructurally, the tumor cells were characterized by various vesicles and scanty microfilaments in their cytoplasm.
