Glycogen Accumulation in Axons of Canine Sympathetic Ganglion

Abstract

PAS positive deposits in sympathetic ganglia were detected in two adult dogs. The deposits were light microscopically observed in perikarya and nerve fibers. They were clearly digested by α amylase. Ultrastructurally the deposits mainly consisted of excessive glycogen accumulation and mitochondria in enlarged axons. Glycogen particles mostly showed low electron-density. Intracytoplasmic deposits at the light microscopy were identical with axonal ones which caved in the perikaryon.