Abstract
A 6-month-old puppy died after exhibiting high fever, diarrhea, and respiratory symptoms and was histologically diagnosed as nocardiosis. Necropsy revealed nodular lesions in the thoracic and visceral organs. Histologically, granulomatous lesions were seen in the liver, cerebrum, cerebellum, pancreas, spleen, myocardium, kidneys, diaphragm, gastrocolic omentum, and lungs. They were characterized by central necrosis surrounded by epithelioid cells, lymphocytes, and neutrophils. Gram-positive, mildly acid-fast, filamentous, branching organisms were detected in the lesions.