Abstract
Ultracytochemical localization of K+-dependent p-nitrophenyl-phosphatase (p-NPPase) activity using Mayahara's method was investigated on the choroid plexus of N-methylnitrosourea (MNU)-induced dysgenetic hydromicrocephalic rat offsprings aged 12 weeks. The reaction sites were characteristically observed in lysosomes, multivesicular bodies, coated vesicles and on basal infoldings in the epithelial cells, in microvesicles in the interstitial cells, and in an increasing number of pinocytotic vesicles and along junctional complex in the capillary endothelial cells. These changes suggest that leaking blood components in choroidal edema might pass the choroidal cells.
