Abstract
A study was performed to assess use of tolazoline as an antagonist of xylazine in cattle. Intravenous injection of tolazoline markedly reduced the recovery period from sedation and analgesia when given 15 min after intravenous injection of xylazine in comparison with those that received xylazine+Ringer's solution. Rumen hypomotility and salivation evoked by xylazine were substantially reduced by tolazoline. These results indicate potential usefulness of tolazoline as an antagonist of xylazine in cattle.