Circulating Immune Complex Levels in Cows with Enzootic Bovine Leukosis

Abstract

Circulating immune complex (CIC) levels of sera from cattle with enzootic bovine leukosis (EBL) and bovine leukemia virus (BLV) negative healthy cows were quantified by a polyethylene glycol turbidity method. Sera from EBL cows and those from EBL cows with membranous glomerulonephritis showed significantly higher level of CIC when compared to that of control normal cows (p<0.05). The CIC of sera from EBL cows showed inhibitory effect to mitogen-induced blastogenesis of normal bovine lymphocytes.