Abstract
A case of bovine uterine adenocarcinoma is described in an aged Holstein Cow. Neoplastic lesions were found in the uterus, pelvic lymph nodes and lungs and consisted of neoplastic glandular tissues supported by much proliferation of dense collagenous connective tissues. The neoplastic cells were characterized by microvilli with prominent filamentous core rootlets and glycocalyceal bodies in the acinar spaces. Stromal cells with lipofuscin were present near the neoplastic glands and the origin was discussed.