A Case of Nephrotic Syndrome Effectively Treated with Saiko-Shimotsu-to with Uzu and Chorei-to without Kasseki

Abstract

I report a case of nephrotic syndrome which responded to Saiko-shimotsu-to with Uzu and Chorei-to without Kasseki. About eight months ago before visiting clinic, a 56-year-old male patient underwent a regular health examination, which took place at the Agricultural Cooperative Association. He was found to have proteinuria. He was diagnosed as having nephrotic syndrome and was treated accordingly. However, he did not respond to various types of treatment, and his conditions aggravated. Severe edema, proteinuria, and hypoproteinemia were noted. When Saiko-shimotsuto was given, he improved a little. When the above formulation was given, these signs were cleared completely. When we reduced the doses of Uzu and Akyo, these signs aggravated, indicating that these ingredients play an important role in improving such signs. Although it has occasionally been reported that Saiko-shimotsu-to is used for gastric ulcer, there is no published record that it has been used for nephrotic syndrome. This case is unique in that the use of Uzu for the syndrome of a Yin disease was effective for proteinuria and hypoproteinemia and that Saiko-shimotsu-to was effective.