Izumi-Fever Aseptic Meningitis

Abstract

In November, 1956, a 3 years and 8 months old female, suffering from an eruptive feverish disease, complicated with nephritis, convulsion and disturbance of consciousness was investigated by the authors. The diagnosis of aseptic meningitis caused by Izumi-fever virus was given. Such a case has never been reported except by Dr. Izumi and a few reporters.
The results were as follows:
1) The eruptions were those of Izumi-fever.
2) Leucocytosis, relative neutrophile leucocytosis and 10% virocytes were observed by means of bloodexamination.
3) The findings of serous meningitis, i.e. the rise of pressure and a slight pleocytosis were obtained by means of spinal fluid examination.
4) The complement fixation test for Izumi-fever turned positive.
5) Hemolytic streptococcus was negative in her pharynx.
6) The rise of A.S.L.O. titer was not noticed.