Case Report of Typhoid and Paratyphoid Fever With High Temperature Treated with Aminobenzyl Penicillin

Abstract

(I) In autumn 1962, two patients suffering from typhoid fever and two from paratyphoid fever were treated with oral dosis of 33-55 mg of Aminobenzyl penicillin per kilogram of body weight daily for 7 days.
In one of the paratyphoid patients, the temperature fell from 40°C to 39°C, which continued, however, for further 4 days.
The other paratyphoid patient on the contrary got higher temperature than he had before the treatment.
The two typhoid patients did not show any tendency of the fall of temperature.
(2) Growth of strains of Salm. typhi and Salm. paratyphi A, B from the patients were inhibited by 0.39-1.56 mcg/ml of aminobenzyl penicillin and 6.25-12.5 mcg/ml of Chloramphenicol.
(3) No side effect was seen in any of the cases.