1965 Volume 39 Issue 9 Pages 330-335
The effect of Erythromycin estolate was observed in 200 patients with bacillary dysentery and following results were obtained.
1) Clinical effects of the drug was not so remarkable. For example, the duration of diarrhea was not markedly reduced.
2) The bacilli of dysentery in feces disappeared within about 1.5 days from the beginning of admission. Reappearance was observed in 11%.
3) Side effects were as follows: gastrointestinal symptoms e.g. anorexia, nausea, abdominal distress in 14% and subclinical disturbances of the liver in some cases. Neither jaundice nor exanthem was observed.
Our observation clearly demonstrates that Erythromycin estolate (Ilosone) is very usefull in the treatment of the bacillary dysentery, especially in mild or symptomless cases and carriers, though clinical effects were not so apparent.
