Journal of the Japanese Association for Infectious Diseases

Show abstractHide abstract

Bacterium antratum has been isolated from blood culture of patients with septicemia at a hospital during the past 10 years period (114 strains in total since 1956) and the results were as follows:
1) Twelve clinical cases in which B. anitratum was isolated from blood stream were presented: In most cases, the patients developed septicemia during the course of the previous diseases.
2) The isolated strains were of an obligate aerobe with a tendency to produce coccoid cell. Themajority of the organisms failed to reduce nitrates, however, oxidized glucose, arabinose, xyrose and garactose, but did not ferment lactose. All the strains produced acid on 10% lactose agar slants, utilized citrate and were nonmotil.
3. Thirty-three among the 55 strains were serologically specific in type 6 (60%) of capsular antisera; the other strains were classified into type 1 (12.7%), type 4 (7.3%), type 10 (7.3%) and nontypable, (12.7%)
4) Most of the strains were found to be sensitive to chloramphenicol, but were highly resistant to streptomycin or colimycin.
5. The authors make proposal that B. anitratum is to be classfied into Genus Achromobacter come.nov. from the viewpoint of its growth characteristics.

View full abstract

Download PDF (999K)

The effect of Erythromycin estolate was observed in 200 patients with bacillary dysentery and following results were obtained.
1) Clinical effects of the drug was not so remarkable. For example, the duration of diarrhea was not markedly reduced.
2) The bacilli of dysentery in feces disappeared within about 1.5 days from the beginning of admission. Reappearance was observed in 11%.
3) Side effects were as follows: gastrointestinal symptoms e.g. anorexia, nausea, abdominal distress in 14% and subclinical disturbances of the liver in some cases. Neither jaundice nor exanthem was observed.
Our observation clearly demonstrates that Erythromycin estolate (Ilosone) is very usefull in the treatment of the bacillary dysentery, especially in mild or symptomless cases and carriers, though clinical effects were not so apparent.

View full abstract

Register with J-STAGE for free!