Journal of the Japanese Association for Infectious Diseases
Online ISSN : 1884-5681
Print ISSN : 0021-4817
ISSN-L : 0021-4817
Studies on Measles Vaccines
(2) A Follow up Study of Children Vaccinated with Live Attenuated Measles Vaccines
Shin ISOMURA
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1966 Volume 40 Issue 1 Pages 1-4

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Abstract

In the interval 1962-1963, about 100 children were immunized by live attenuated measles vaccines.
1) In the following 20 months after vaccination, 57 vaccinees were exposed to natural measles. 4 (7%) in these children suffered from measles, 2 from regular measles; 2 from modified measles. In the control group children dwelling the same area, outbreaks of natural measles were observed. 75% or greater of those suffered from regular measles.
2) In the children not exposed to natural measles, NT antibody level persisted undiminished or slightly decreased in 18 months after administration of live vaccines.
3) The vaccinees resisted firmly against the re-vaccination of live vaccines inoculated in 12 months after first vaccination.
4) Booster effect was observed both after the exposure to natural measles and after the re-vaccination.

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