ウィントマイロンによる細菌性赤痢の治療

抄録

Recently, antibiotic resistant bacillary dysentery has increased in number in Shimizu City, causative strains of them being almost Shigella sonnei.
In the treatment of antibiotic resistant cases (168 in total; 10 manifested cases, 158 healthy carriers) almost due to Shigella sonnei, Wintomylon was found to have good effect in the single use. Daily dose of 50 mg per Kg of Wintomylon was given every 6 hours per day for 5 days successively after admission.
Reappearance rate of Shigella was 1.1 per cent in carriers and 20 per cent in previously manifested one. Side effects were seen in 13 cases (7.7%), in 7 of them, it was vision abnormality.