On Clinical Application of Drug-Resistant Str. Fecalis Medicine. Especially curative application against dysentery.

Abstract

It is demonstrated that CBPR, a biological product which consists of a multiple antibiotic resitant strain of str. fecalis, shows preventive effect against various manifestations such as constipation or other disorders of defecation, which occasionally occur after antibiotic therapy. It is inferred that this is chiefly because the str. fecalis contained alive and endowed with resistancy to each kind of antibiotics such as SM, CP, TC, KM, F, etc., may act effectively for the maintenance of intestinal bacterial flora.
At the same time, it is also recognized that the drug produces no subsidiary effect, and itis suggested that, in the medication, there is no possibility to transmit its resistancy to other intestinal bacilli.
Though the drug can not give an impression to influence directly on dysenteric course itself, it is recognized suggestively that the drug has an allopathic effect for the infantile dia rrhea caused by “indigestion”. To sum up, the clinical peculiarity of this drug lies in the possibility of combined administration together with antibiotics and these characteristics could not be noticedheretofore in any other drugs of this line.