抄録
Several serlogical experiments were carried out to establish a serum reaction specific to epidemic hemorrhagic fever in man.
The results were as follows:
1. Unchanging low precipitating antibody titers in patient sera against supernatant fluid of emulsion of liver released from deceased patient by autopsy, suggested that the reactiossn failed to be a useful method for the diagnosis.
2. The Weil-Felix antibodies in sera from patients in pyrexial stage, to the Proteus vulgaris OX-19, OX-2, and OX-K strains, were also so low that the Weil-Felix reaction was not specific for the disease.
3. Finally, a skin test with antigenic materials prepared by filtrating the liver emulsion in physiological saline solution (as well Ringer's solution or Tyrode's solution) with Chamberland filter, was performed and it was demonstrated that this reaction was useful to differentiate the patients from the controls with other diseases after 24 hours and therefore available for the diagnostic purposes.
