1985 Volume 59 Issue 12 Pages 1191-1197
For the purpose of studying the infection caused by Chlamydia trachomatis (C.trachomatis) in compromised patients with diseases of internal medicine, serum antibodies to C.trachomatis were measured by the method of micro-immunofluorescence test in Japan.
Sera from 76 patients with diabetes mellitus, 80 patients with systemic lupus erythematosus, 18 patients with malignant lymphoma, 10 patients with leukemia, 9 patients with aplastic anemia and 51 healthy individuals were obtained to detect antibodies to C.trachomatis.
The results were as follows:
1) Significant increase in the % postitivity of IgG class antibody was present in patients with diabetes mellitus (32.9%), compared with those of normal controls (11.8%).Especially, poor-controlled diabetic patients had the strong association with the % positivity of IgG class antibody (42.9%), compared with those of normal controls.
2) Slight increase in the % positivity of IgG class antibody was present in patients with malignant lymphoma (27.8%).3) IgM class antibody was also detected in 1 patient with diabetes mellitus, 1 patient with systemic lupus erythematosus and 1 patient with malignant lymphoma.The patient with malignant lymphoma showed pneumonia.C.trachomatis was suspected as the causative organism of such infection.
