Staphylococcus aureus Bacteremia: Clinical-Bacteriological Study of 28 Cases

Abstract

The medical records of 28 patients with Staphylococcus aureus bacteremia at the Juntendo University Hospital during a 7 year study period, 1976 to 1982, were reviewed. Bacteremias with community acquired in 12 patients and hospital acquired in 16 patients were seen.Most of the patients were 40 years of age or older.Ten of 12 patients with community acquired bacteremia had primary foci of staphylococcal infection occurring secondary to bacteremia. Patients with hospital acquired bacteremia had more serious underlying conditions than those with community acquired bacteremia.Seven of 16 patients with hospital acquired bacteremia had a malignancy and five were associated with an infected intravenous catheter for IVH.There was no patient with endocarditis secondary to Staphylococcal aureus bacteremia. Penicillin-G and ampicillin were not effective for most isolates of S. aureus from blood cultures, whereas cloxacillin, sulbenicillin, cefazolin, cefmetazole and cefotiam had an antimicrobial activity for the isolates.