A surgical case of solitary lymph node metastatic recurrence of combined hepatocellular and cholangiocarcinoma after hepatectomy

Abstract

A 79-year-old woman who was undergone hepatic resection for combined hepatocellular and cholangiocarcinoma. During follow-up, her serum AFP and PIVKA-II were found to be elevated. Abdominal computed tomography (CT) showed a solitary tumor. She had no recurrence in the liver or other organs. Under a diagnosis of solitary lymph node metastatic recurrence, we excised the lymph node. Histological examination showed lymph node metastasis of HCC component of combined hepatocellular and cholangiocarcinoma. Serum AFP and PIVKA-II decreased postoperatively. No signs of recurrence were seen in follow-up 4 months after surgery. We report a surgical case of solitary lymph node metastatic recurrence of combined hepatocellular and cholangiocarcinoma after hepatectomy with a review of the literature.