A case of autoimmune hepatitis diagnosed with elevated value of CA125, ascites, metrorrhagia

Abstract

A 60-year-old woman, who had seen in a previous hospital with chief complaints of general malaise, abdominal bloating, weight gain, and metrorrhagia in August 201X, was referred to our hospital because of large ascites and elevated value of CA125. CT and transvaginal ultrasound imaging of gynecologic malignancy and ascitic fluid cytology were all negative. Her liver function had been impaired since the initial visit, but elevated level of ANA and IgG were observed after hospitalization. Histological changes obtained from liver biopsy, which was done after the management of ascites, were consistent with those of autoimmune hepatitis and cirrhosis. After treatment, CT showed ascites had disappeared in January 201X+1, and CA125 was reduced to normal level in May 201X+1.