Abstract
1) According to the statistical analysis of the answer of 72 persons, whose spouses were HB antigen carriers, ten patients (13.9% of total) had suffered from the liver disease after their marriage. Interesting enough, one of these 10 patients died of liver cirrhosis 7 years after marriage.
2) HB antigen could not be detected in none of twenty-six cases, whose spouses were HB antigen carriers, whereas 12 cases (46.2%) revealed HB antibody. This incidence (46.2%) of HB antibody positivity was significantly higher than that (23.1%) among the general population in same city.
3) 6 out of 10 hepatitis cases with positive HB antigen had supouses who were supposed to be HB antigen carrier with high antigen titer.
And the most interesting thing in this report is that HB antigen associated hepatitis developed within one year of the marriage with the spouses who were HB antigen carriers.